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25/03/21 09:04 from Publication digest (http://feed.informer.com/digests/PG3LWREPDK/feeder)

Как и в любой структуре, в российской армии существует определенная иерархия. В данном случае «пирамида» представляет собой военные должности и соответствующие им армейские звания. При этом в качестве отличительных знаков на форме военнослужащих предусмотрены погоны . Сегодня поговорим о том, какие...

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Posted: 25 Mar 2021 11:02 AM PDT

german_bulgarian.deacademic.com

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Тромб

Posted: 25 Mar 2021 11:04 AM PDT

Российский спутник "Канопус–В" снял судно Evergiven компании Evergreen застопорившее все движение в Суэцком канале. Все суда идущие из Европы в Китай и обратно теперь ждут, когда же Evergiven стащат с мели. Фотография снята мультиспектральной камерой спутника. У "Канопуса–В" есть еще и панхроматическая камера с большим разрешением, но она дает на выходе черно–белые снимки.

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Resolutions Passed At The Annual General Meeting

Posted: 25 Mar 2021 10:53 AM PDT

Orphazyme A/SCompany announcement                                                                                       No. 08/2021                                                                                                            Company Registration No. 32266355

Copenhagen, Denmark, March 25, 2021 - Orphazyme A/S (ORPHA.CO; ORPH) (the "Company"), a late-stage biopharmaceutical company pioneering the Heat-Shock Protein response for the treatment of neurodegenerative orphan diseases, today held its Annual General Meeting, at which the Annual General Meeting:

  • Took note of the Board of Directors' report on the Company's activities in the past financial year;
  • Adopted the Company's Annual Report 2020;
  • Adopted that the loss related to the financial year 2020 is carried forward;
  • Granted discharge of liability to the Board of Directors and the Executive Management in relation to the Annual Report 2020;
  • Approved the remuneration report for 2020 in the advisory vote;
  • Approved the remuneration of the Board of Directors for the current financial year;
  • Re-elected Georges Gemayel, Bo Jesper Hansen, Anders Hedegaard, Carrolee Barlow, Catherine Moukheibir, Martijn Kleijwegt, Martin Bonde, and Rémi Droller as members of the Board of Directors;
  • Elected Stephanie Okey as new member of the Board of Directors;
  • Re-elected EY Godkendt Revisionspartnerselskab as the Company's auditor in accordance with the recommendation from the Audit Committee;
  • Adopted an authorization to the Board of Directors to approve the acquisition of treasury shares in the period until March 25, 2026 with a total nominal value of up to 10% of the share capital of the Company subject to the Company's holding of treasury shares after such acquisition does not exceed 20% of the Company's share capital;
  • Approved certain adjustments to the Company's Remuneration Policy, including (i) adjustments to allow for a share-based incentive program to the Executive Management and certain employees comprising restricted share units and performance share units, (ii) adjustment of the shareholding requirement for the Executive Management, (iii) adjustment of the claw back clause with the purpose of aligning the clause with the revised Danish Recommendations on Corporate Governance and (iv) adjustment of the situations under which accelerated vesting may occur;
  • Adopted an amendment to Article 3.1 of the Articles of Association regarding renewal and extension of the existing authorization to the Board of Directors to increase the Company's share capital without pre-emption rights for existing shareholders by up to a nominal amount of DKK 6,989,767 and the deletion of Article 3.1.1; and
  • Adopted an authorization to the Board of Directors included in a new Article 3.5 of the Articles of Association to increase the share capital in the period until March 25, 2026 without pre-emption rights for existing shareholders by up to a nominal amount of DKK 1,300,000 in connection with the issue of new shares to members of the Board of Directors, executives and/or employees of the Company subject to a total cap of nominally DKK 2,000,000 for both authorizations under the current Article 3.2 and the new Article 3.5 of the Articles of Association.

After the Company's Annual General Meeting was held, the Board of Directors constituted itself by appointing Georges Gemayel as Chairman and Bo Jesper Hansen as Deputy Chairman of the Board of Directors.

For additional information, please contact

Orphazyme A/S

Anders Vadsholt, Interim CEO and CFO          +45 28 98 90 55

About Orphazyme A/S Orphazyme is a late-stage biopharmaceutical company pioneering the Heat Shock Protein response for the treatment of neurodegenerative orphan diseases. The company is harnessing amplification of Heat Shock Proteins (or HSPs) in order to develop and commercialize novel therapeutics for diseases caused by protein misfolding, protein aggregation, and lysosomal dysfunction, including lysosomal storage diseases and neuromuscular degenerative diseases. Arimoclomol, the company's lead candidate, is in clinical development for four orphan diseases: Niemann-Pick disease type C (NPC), Amyotrophic Lateral Sclerosis (ALS), Inclusion Body Myositis (IBM) and Gaucher disease. Orphazyme is headquartered in Denmark and has operations in the U.S. and Switzerland. Orphazyme's shares are listed on Nasdaq U.S. (ORPH) and Nasdaq Copenhagen (ORPHA). 

About arimoclomol  Arimoclomol is an investigational drug candidate that amplifies the production of Heat Shock Proteins (HSPs). HSPs can rescue defective misfolded proteins, clear protein aggregates, and improve the function of lysosomes. Arimoclomol is administered orally and has now been studied in seven phase 1, four phase 2 and one pivotal phase 2/3 trial. Arimoclomol is in clinical development for NPC, Gaucher Disease, IBM, and ALS. Arimoclomol has received orphan drug designation (ODD) for NPC, IBM, and ALS in the US and EU. Arimoclomol has received fast-track designation (FTD) from the U.S. Food and Drug Administration (FDA) for NPC, IBM, and ALS. In addition, arimoclomol has received breakthrough therapy designation (BTD) and rare-pediatric disease designation (RPDD) from the FDA for NPC.

Forward-looking statement This company announcement may contain certain forward-looking statements, including in respect of the anticipated commercialization of arimoclomol. Although the Company believes its expectations are based on reasonable assumptions, all statements other than statements of historical fact included in this company announcement about future events are subject to (i) change without notice and (ii) factors beyond the Company's control. These statements may include, without limitation, any statements preceded by, followed by, or including words such as "target," "believe," "expect," "aim," "intend," "may," "anticipate," "estimate," "plan," "project," "will," "can have," "likely," "should," "would," "could", and other words and terms of similar meaning or the negative thereof. Forward-looking statements are subject to inherent risks and uncertainties beyond the Company's control that could cause the Company's actual results, performance, or achievements to be materially different from the expected results, performance, or achievements expressed or implied by such forward-looking statements, including the risk that applicable regulatory authorities fail to approve arimoclomol on the anticipated timeline or at all. Except as required by law, the Company assumes no obligation to update these forward-looking statements publicly, or to update the reasons actual results could differ materially from those anticipated in the forward-looking statements, even if new information becomes available in the future.

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Зимние птицы 5

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Cats в гостях на Blue

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Lonely Night by RicoDZ

По наводке @zapovednik_slonov и @kindzarp

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salir bordado - Diccionario del Argot "El Sohez"

Posted: 25 Mar 2021 10:37 AM PDT

29.03.2020 — bordado, salir bordado expr. salir bien. ❙ «Paco, te ha salido bordado. Me dijo que te felicitara...» Luis Mateo Díez, La fuente de la edad, 1986, RAE CREA.

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Daily Deals (3-25-2021)

Posted: 25 Mar 2021 10:55 AM PDT

Amazon is running a sale on Aukey true wireless earbuds, with some models selling for as little as $21. The sale also includes some of the best prices I've seen to date on earbuds with active noise cancellation. One pair is selling for just $30, while a set with hybrid ANC using external and internal […]

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plain-pied - translate.academic2.ru

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il est entré de plain-pied dans le sujet — он легко́ овладе́л те́мой

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The Sterling Group Announces Promotions

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Ролевая стратегия в антураже XVII века Black Legend вышла на ПК и консолях

Posted: 25 Mar 2021 10:51 AM PDT

Компания Warcave выпустила пошаговую ролевую стратегию Black Legend, действие которой разворачивается в XVII веке. Игра уже доступна на ПК, Xbox One, Xbox Series X и S, PlayStation 4, PlayStation 5 и Nintendo Switch. События Black Legend разворачиваются на улицах вымышленного города Грант с архитектурой в шотландском стиле. Алхимик по имени Мефисто окутал поселение густым туманом, который сводит с ума жителей. Культисты, поклоняющиеся этому туману, захватили контроль над улицами и ввергли город в хаос. Вам предстоит восстановить порядок в Гранте и сразиться с сектой в пошаговых боях, которые сочетают в себе классическую механику ролевой стратегии и систему алхимии.

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PPL Hosting Annual Supplier Diversity Conference On April 23

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Где сидит Парфёнов

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العربية: المادة: مورفولوجيا البيض جولة التماس ...

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На бреющем

Posted: 25 Mar 2021 11:10 AM PDT

Еще любопытное видео от Максима про очередной развод на автохлам

Posted: 25 Mar 2021 11:10 AM PDT

http://youtu.be/L0jZ8R7Rhb4

Человек поехал в салон за новым автомобилем стоимостью 1 200 000 руб.
В результате купил машину, которая была списана на тотал за общую сумму 3 000 000 руб.

Вот, неужели так свербило?

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guitar.d3.ru — Ничего не найдено!

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Post from 25.03.2021 : БроЗаДОБРО

Posted: 25 Mar 2021 11:02 AM PDT

Cisco Gets Boost as Goldman Sees Reopening Opportunity

Posted: 25 Mar 2021 11:02 AM PDT

Но есть надежда!

Posted: 25 Mar 2021 11:04 AM PDT

оберточная бумага, линеры, 15х18

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pioresnada - Diccionario Lunfardo

Posted: 25 Mar 2021 10:37 AM PDT

Mira otros diccionarios: pioresnada — pareja; cf. pololo, yunta, media naranja, pierna, peor es nada, peor es nada; iba de lo mejorcito con mi pioresnada por el ...

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